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Applied Physiology
 

Overview

Applied Physiology incorporated in January 2004,  to invent, develop and commercialise smart medical devices and software for the critical care markets. Substantial work has been performed in the last 3 years prototyping and testing products; analysing market opportunities and developing its business strategy. Further, Applied Physiology brings together years of medical, R&D and commercial experience of its founders Dr Geoffrey Parkin and Dr Mark Leaning.

Applied Physiology aims to address the need for improved monitoring and control in healthcare – particularly where trauma or disease has temporarily or permanently de-stabilised the body’s normal homeostatic mechanisms. Related to this is the need for achieving greater productivity in healthcare.  Within the critical care specialty, Applied Physiology currently has three (3) products that are at a late stage of R&D, prototyping and clinical testing.
Depending on the product, Applied Physiology uses a combination of technologies. These include dynamic mathematical models of the underlying physiology, model adaptation and control algorithms, electro-medical devices, software device interfacing and networking. The inclusion of physiological models is a key differentiating feature of the business. Simply put, these “system models” are the smarts in Applied Physiology’s products.
The company has exclusive rights to a range of existing intellectual property (including patents, registered designs, and copyright) and is building a substantial portfolio of new wholly owned IP.

Business Opportunities (i.e Partner, Joint Venture, Distributor, Agent, End User)

Applied Physiology is currently undertaking registration enabling clinical studies of their flagship product Navigator and plan to submit for CE and TGA approval in 2008. 

Applied Physiology is anticipating marketing Navigator©, into Europe, UK and Australia and NZ in late 2008 and is looking for credentialed companies as distributor partners in the critical care space in those geographies .

Technology/Products and Services Description

AP’s core product the Navigator©, is a physiologically integrated, clinical software, designed to assist clinicians in improving the management of the systemic circulatory state in the critically ill patient.
Navigator may assist the clinician improve circulatory management by:

  • Permitting easy definition of the target area for the desired circulation 
  • Providing continuous numerical description of the volume, resistance and cardioactive states, allowing the clinician to instantly design (prescribe) and measure the effect of therapy 
  • Early numerical identification of problems and variance 
  • Permitting safe minimisation of heart output power with potential to reduce cardiac events

As a consequence of improved circulatory management, potential clinical benefits may include:

  • Reduced time to acquire and hold the desired circulation 
  • Continuous adaptation of therapeutic guidance to the changing patient and avoidance of inappropriate therapy

Competitive Advantages

Navigator© is a physiologically integrated, real time, clinical software system that assists clinicians in managing the circulatory system of the critically ill. Based on rigorous mathematical models and extensive clinical experience, Navigator© is a real-time graphical representation of the patients circulatory system. Navigator© allows the Clinician to set individual patient haemodynamic targets and then see at a glance the patients current haemodynamic state in relation to those desired targets. Navigator© also has inbuilt decision making support that suggests the next order of therapy to move the patient towards the target zone. Navigator© is an innovative and exciting new circulatory system guidance tool that assists Clinician’s to improve circulatory system management and patient care.


Website address: www.applied-physiology.com

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