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| TetraQ |
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TetraQ is an Australian contract research organisation providing a range of high-quality, integrated and tailored preclinical services (ADME, Efficacy, Pharmaceutics, Toxicology) globally to the pharmaceutical and biotechnology industries. We work with companies developing new drugs, seeking assistance with selecting a drug candidate or requiring preclinical drug characterisation.
We aim to provide a ‘one-stop’ service for our clients which is backed by a highly skilled scientific team with a wealth of experience in all four disciplines of preclinical development. We take the time to understand your business needs and provide comprehensive tailored solutions either in-house or through our network.
In addition to providing a range of contract services to clients, we can also consult to your business by providing expert opinions, reviewing and interpreting data, reviewing product development plans, assisting in due diligence. We can also advise on early stage drug development activities including regulatory strategy.
TetraQ provides contract services to clients in the pharmaceutical, nutraceutical and biotechnology industries who require early stage drug development services.
TetraQ also seeks collaborative relationships with other contract research organisations in these industries
TetraQ - ADME
- In vitro and in vivo services investigating absorption, metabolism, distribution and elimination
- Bioanalysis of biological samples including urine and plasma
- Pharmacokinetic and bioavailability studies in rodents
- Assay development and validation
- Metabolite identification and profiling
TetraQ - Efficacy
- Specialising in in vivo animal models of efficacy in various disease states
- In vivo rodent models of pain (sensitivity and perception, acute stimulus, acute and chronic inflammatory pain, neuropathic pain
- In vitro opioid agonist and antagonist screening assay
- CNS models including Alzheimer's Disease, Parkinson's Disease and multiple sclerosis
- Other models - obesity, diabetes, inflammatory bowel disease, arthritis and stroke.
TetraQ - Pharmaceutics
- Characterisation (FTIR,UV,NMR,MS)
- Physicochemical profiling, solubility
- Structure elucidation
- Stability studies (chemical and biological)
- In vitro absorption studies (Caco-2 assays)
- Formulation development
- Dissolution testing
- Analytical method development and validation
- Specialised peptide synthesis services
TetraQ - Toxicology
- In vitro and in vivo toxicology services - cytotoxicity assays, genotoxicity assays (Ames test, & Micronucleus Test);
- Maximum tolerated dose studies
- In vivo acute and chronic toxicity
- Cytogenetic assays
- Offer clients tailored solutions, not just a menu of choices
- Assist clients with data interpretation to facilitate and guide timely decision-making
- Quality science behind all services (no short cuts)
- Highly skilled scientific and commercial team
- Services backed by a leadership team with wealth experience in all 4 areas of preclinical drug development
- Are a ‘one-stop shop’ to simplify early stage drug development
www.tetraq.com.au
 
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